Inter-disciplinary
Research Group

Focused on understanding, diagnosing and treating aortic diseases through novel approaches
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INTRODUCING OUR GROUP

About LABB
Group

Liverpool Aortic Biomechanics and Biochemistry Research Group (LABB) is an inter-disciplinary research group spanning expertise in materials science, biochemistry, vascular surgery and applied mathematics. Our interests span a range of areas within cardiovascular medicine and science but are largely focused on aortic dissection and ascending aortic aneurysms.

Biomechanics


We focus on understanding bio-mechanical changes that occur with aortic pathology through micro- and nano- mechanical testing methods.


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Biochemistry


We  focus on studying the role of extracellular matrix proteins and amyloid deposits on the normal function of the aorta.


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Statistical Modelling


We apply machine learning approaches to develop prediction models for risk of aortic pathology such as aneurysms.


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Our Team



Reader (Associate Professor)

Dr Riaz Akhtar

His research group focusses on soft tissue micromechanics and structure-property relationships in aortic tissue. He is a Reader in Biomedical Engineering at University of Liverpool.


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Senior Lecturer

Dr Jill Madine

Her research group at the University of Liverpool has a wide interest in amyloid protein diseases and elucidating the factors that contribute to the pathogenicity associated with these diseases.


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Consultant Vascular Surgeon (Honorary Professor)

Prof. Mark Field

Cardiac Surgery training took place in Nottingham, Sheffield and Liverpool and finished in 2009. He was appointed a consultant at Liverpool Heart and Chest Hospital in 2009.



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Partnership

Our Funders

We offer our thanks to all our valued funders for their support and commitment.


The Leverhulme Trust was established by the Will of William Hesketh Lever, the founder of Lever Brothers.


Engineering is at the heart of our nation , transforming ideas and materials into global infrastructure, products and services.


We are the nation’s heart charity and the largest independent funder of cardiovascular research.

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The Aortic Dissection Charitable Trust is the UK and Ireland charity uniting patients, families

Our Publications

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DR. Riaz Akhtar

Microcalcification and Thoracic Aortopathy: A Window Into Disease Severity


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DR. Riaz Akhtar

Time-dependent mechanical behaviour of the aortic chronic dissection flap


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DR. Jill Madine

Exploring the potential of rapid evaporative ionization mass spectrometry (Intelligent Knife)


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MR. Mark Field

Bicuspid valve aortopathy is associated with distinct patterns of matrix degradation


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Latest News


October 26, 2023by Riaz

The LABB Group took part in a highly successful multi-disciplinary workshop on aortic diseases with Fudan University and Zhongshan Hospital, Shanghai from 20th – 24th September 2023. Drs Riaz Akhtar (Liverpool) and Baolei Guo were successful in obtaining a Royal Society International Exchange grant to setup the workshop and attendees including researchers from Imperial College […]

October 20, 2023by Riaz

Save the Date! We are pleased to announce that “Aorta: Structure to Rupture 2024” will take place once again in Liverpool on Thursday 20th June 2024. This is always an exciting inter-disciplinary meeting bringing together engineers, biologists, and clinicians to discuss state-of-the-art research in aortic disease. We encourage early career researchers to take part and […]

September 16, 2023by Riaz

Congratulations to Bojin Marinov who won the best poster prize for his first year work looking at collagen fibril degradation in bicuspid aortic valve patients at BioMedEng 2023 conference which was held in Swansea, 14 – 15 September 2023. Bojin is a PhD student in the Department of Materials, Design and Manufacturing Engineering working under the supervision […]

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Contact Us


Our Address

University of
Liverpool Brownlow Hill,
Liverpool L69 3BX,
United Kingdom


Call Us

+44 (0)151 794 2000


E-mail

info@labb-group.com


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Copyright @2023  LABB-Group. All rights reserved.